Levofloxacin (Standard)

Levofloxacin (Standard) is the analytical standard of Levofloxacin. This product is intended for research and analytical applications. Levofloxacin ((-) -Ofloxacin) is an orally active antibiotic and is active against both Gram-positive and Gram-negative bacteria. Levofloxacin inhibits the DNA gyrase and topoisomerase IV. Levofloxacin can be used for chronic periodontitis, airway inflammation and BK Viremia research. Levofloxacin shows anti-orthopoxvirus activity[1][2][3][4][5].

Product Specifications

CAS Number

[100986-85-4]

Product Name Alternative

(-) -Ofloxacin (Standard)

UNSPSC

12352005

Target

Antibiotic; Bacterial; DNA/RNA Synthesis; Orthopoxvirus; Reference Standards; Topoisomerase

Type

Reference Standards

Related Pathways

Anti-infection; Cell Cycle/DNA Damage; Others

Applications

COVID-19-anti-virus

Field of Research

Infection; Cancer

Assay Protocol

https://www.medchemexpress.com/levofloxacin-standard.html

Purity

99.96

Solubility

10 mM in DMSO

Smiles

O=C(C(C1=O)=CN2[C@@H](C)COC3=C(N4CCN(C)CC4)C(F)=CC1=C23)O

Molecular Formula

C18H20FN3O4

Molecular Weight

361.37

References & Citations

[1]Rand A, et al. Effect of levofloxacin on some body tissues in mice. Effect of levofloxacin on some body tissues in mice. Iraqi Journal of Veterinary Sciences, 2021.|[2]Smee DF, et al. A review of compounds exhibiting anti-orthopoxvirus activity in animal models. Antiviral Res. 2003 Jan;57 (1-2) :41-52.|[3]JI B, et al. In vitro and in vivo activities of levofloxacin against Mycobacterium tuberculosis. Antimicrob Agents Chemother. 1995 Jun;39 (6) :1341-4. |[4]Drlica K, et al. DNA gyrase, topoisomerase IV, and the 4-quinolones. Microbiol Mol Biol Rev. 1997 Sep;61 (3) :377-92.