Milategrast

Milategrast is useful as cell adhesion inhibitor or cell infiltration inhibitor. Milategrast in vitro inhibites the adhesion of Jurkat cells to human fibronectin with an IC50 of [1].

Product Specifications

CAS Number

[859217-52-0]

Product Name Alternative

E6007

UNSPSC

12352005

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/milategrast.html

Purity

99.94

Solubility

DMSO : 5 mg/mL (ultrasonic; warming; adjust pH to 2-3 with HCl; heat to 60°C)

Smiles

CC1(C)CC(C)(C)CC(C2=CC=CC=C2N3CCN(CC4CC4)CC3)C1

Molecular Formula

C24H38N2

Molecular Weight

354.57

References & Citations

[1]Kotake, et al.Preparation of various crystal forms and salts of 1-cyclopropylmethyl-4-[2- (3,3,5,5-tetramethylcyclohexyl) phenyl]piperazine for treating or preventing various inflammatory diseases and autoimmune diseases.WO2006068058A1|[2]Huang H, et al. Microplastics in the bloodstream can induce cerebral thrombosis by causing cell obstruction and lead to neurobehavioral abnormalities. Sci Adv. 2025 Jan 24;11 (4) :eadr8243.