Milategrast
Milategrast is useful as cell adhesion inhibitor or cell infiltration inhibitor. Milategrast in vitro inhibites the adhesion of Jurkat cells to human fibronectin with an IC50 of [1].
Product Specifications
CAS Number
[859217-52-0]
Product Name Alternative
E6007
UNSPSC
12352005
Target
Others
Type
Reference compound
Related Pathways
Others
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/milategrast.html
Purity
99.94
Solubility
DMSO : 5 mg/mL (ultrasonic; warming; adjust pH to 2-3 with HCl; heat to 60°C)
Smiles
CC1(C)CC(C)(C)CC(C2=CC=CC=C2N3CCN(CC4CC4)CC3)C1
Molecular Formula
C24H38N2
Molecular Weight
354.57
References & Citations
[1]Kotake, et al.Preparation of various crystal forms and salts of 1-cyclopropylmethyl-4-[2- (3,3,5,5-tetramethylcyclohexyl) phenyl]piperazine for treating or preventing various inflammatory diseases and autoimmune diseases.WO2006068058A1|[2]Huang H, et al. Microplastics in the bloodstream can induce cerebral thrombosis by causing cell obstruction and lead to neurobehavioral abnormalities. Sci Adv. 2025 Jan 24;11 (4) :eadr8243.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
Phase 2
Available Sizes
Curated Selection
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