ML167
Product Specifications
UNSPSC Description
ML167 is a highly selective Cdc2-like kinase 4 (Clk4) inhibitor with IC50 of 136 nM, >10-fold selectivity for closely related kinases Clk1, Clk2, Clk3 and Dyrk1A/1B[1].
Target Antigen
CDK; DYRK
Type
Reference compound
Related Pathways
Cell Cycle/DNA Damage;Protein Tyrosine Kinase/RTK
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/ML167.html
Solubility
DMSO : 16.67 mg/mL (ultrasonic)
Smiles
OCC1=CC=C(C2=CC3=C(NCC4=CC=C(C)O4)N=CN=C3C=C2)O1
Molecular Weight
335.36
References & Citations
[1]Rosenthal AS, et al. An inhibitor of the Cdc2-like kinase 4 (Clk4).
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-15951/ML167-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-15951/ML167-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1285702-20-6
Available Sizes
Curated Selection
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