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ML167

Product Specifications

UNSPSC Description

ML167 is a highly selective Cdc2-like kinase 4 (Clk4) inhibitor with IC50 of 136 nM, >10-fold selectivity for closely related kinases Clk1, Clk2, Clk3 and Dyrk1A/1B[1].

Target Antigen

CDK; DYRK

Type

Reference compound

Related Pathways

Cell Cycle/DNA Damage;Protein Tyrosine Kinase/RTK

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/ML167.html

Solubility

DMSO : 16.67 mg/mL (ultrasonic)

Smiles

OCC1=CC=C(C2=CC3=C(NCC4=CC=C(C)O4)N=CN=C3C=C2)O1

Molecular Weight

335.36

References & Citations

[1]Rosenthal AS, et al. An inhibitor of the Cdc2-like kinase 4 (Clk4).

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-15951/ML167-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-15951/ML167-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

1285702-20-6

Available Sizes

Curated Selection

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