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STING agonist-8 (dihydrochloride)

Product Specifications

UNSPSC Description

STING agonist-8 dihydrochloride (compound 5-AB) is a potent STING agonist with an EC50 of 27 nM in THP1-Dual KI-hSTING-R232 cells[1].

Target Antigen

STING

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/sting-agonist-8-dihydrochloride.html

Solubility

DMSO : 5 mg/mL (ultrasonic;warming;heat to 60°C)

Smiles

O=C(C1=CC(C)=NN1CC)NC2=NC3=CC(C(N)=O)=CN=C3N2C/C=C/CN4C5=C(OCCCC6CNC6)C=C(C(N)=O)C=C5C7=CN=C(C8=CC(C)=NN8CC)N=C74.[H]Cl.[H]Cl

Molecular Weight

871.82

References & Citations

[1]Heterocyclic compounds as sting modulators. WO2021239068A1.

Shipping Conditions

Blue Ice

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-144168A/STING-agonist-8-dihydrochloride-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-144168A/

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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