STING agonist-8 (dihydrochloride)
STING agonist-8 dihydrochloride (compound 5-AB) is a potent STING agonist with an EC50 of 27 nM in THP1-Dual KI-hSTING-R232 cells[1].
Product Specifications
UNSPSC
12352005
Target
STING
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sting-agonist-8-dihydrochloride.html
Purity
98.30
Solubility
DMSO : 5 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(C1=CC(C)=NN1CC)NC2=NC3=CC(C(N)=O)=CN=C3N2C/C=C/CN4C5=C(OCCCC6CNC6)C=C(C(N)=O)C=C5C7=CN=C(C8=CC(C)=NN8CC)N=C74.[H]Cl.[H]Cl
Molecular Formula
C41H48Cl2N14O4
Molecular Weight
871.82
References & Citations
[1]Heterocyclic compounds as sting modulators. WO2021239068A1.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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