AT-1002 (TFA)
AT-1002 TFA, a 6-mer synthetic peptide[1], is a tight junction regulator and absorption enhancer[2].
Product Specifications
Product Name Alternative
6-Nitroveratraldehyde
UNSPSC
12352005
Target
Gap Junction Protein
Type
Reference compound
Related Pathways
Cytoskeleton
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Assay Protocol
https://www.medchemexpress.com/AT-1002_TFA.html
Purity
99.72
Solubility
DMSO : 33.33 mg/mL (ultrasonic) |H2O : 1 mg/mL (ultrasonic)
Smiles
N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CS)C(N[C@@H]([C@H](CC)C)C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O
Molecular Formula
C34H54F3N9O9S
Molecular Weight
821.91
References & Citations
[1]Li M, et al. Structure-activity relationship studies of permeability modulating peptide AT-1002. Bioorg Med Chem Lett. 2008 Aug 15;18 (16) :4584-6.|[2]Gopalakrishnan S, et al. Mechanism of action of ZOT-derived peptide AT-1002, a tight junction regulator and absorption enhancer. Int J Pharm. 2009 Jan 5;365 (1-2) :121-30.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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