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AT-1002 (TFA)

AT-1002 TFA, a 6-mer synthetic peptide[1], is a tight junction regulator and absorption enhancer[2].

Product Specifications

Product Name Alternative

6-Nitroveratraldehyde

UNSPSC

12352005

Target

Gap Junction Protein

Type

Reference compound

Related Pathways

Cytoskeleton

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/AT-1002_TFA.html

Purity

99.72

Solubility

DMSO : 33.33 mg/mL (ultrasonic) |H2O : 1 mg/mL (ultrasonic)

Smiles

N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CS)C(N[C@@H]([C@H](CC)C)C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)=O.OC(C(F)(F)F)=O

Molecular Formula

C34H54F3N9O9S

Molecular Weight

821.91

References & Citations

[1]Li M, et al. Structure-activity relationship studies of permeability modulating peptide AT-1002. Bioorg Med Chem Lett. 2008 Aug 15;18 (16) :4584-6.|[2]Gopalakrishnan S, et al. Mechanism of action of ZOT-derived peptide AT-1002, a tight junction regulator and absorption enhancer. Int J Pharm. 2009 Jan 5;365 (1-2) :121-30.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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