LDLR, Mouse (Biotinylated, A23V, C27G, HEK293, His)
LDLR Protein crucially binds to LDL, transporting cholesterol through endocytosis. Clustering into clathrin-coated pits initiates internalization. Interactions with DAB2, LDLRAP1, ARRB1, SNX17, and immature PCSK9 contribute to its functional versatility. The NPXY motif interaction is impaired by tyrosine phosphorylation. LDLR Protein, Mouse (Biotinylated, A23V, C27G, HEK293, His) is the recombinant mouse-derived LDLR protein, expressed by HEK293 , with C-His labeled tag and A23V, C27G mutation.
Product Specifications
Product Name Alternative
LDLR Protein, Mouse (Biotinylated, A23V, C27G, HEK293, His), Mouse, HEK293
UNSPSC
12352202
Type
Recombinant Proteins
Assay Protocol
https://www.medchemexpress.com/cytokines/ldlr-protein-mouse-biotinylated-a23v-c27g-hek293-his.html
Molecular Formula
16835 (Gene_ID) P35951/NP_034830.2 (A22-R790, A23V, C27G) (Accession)
Molecular Weight
Approximately 85.7 kDa
Shipping Conditions
Dry ice.
Scientific Category
Recombinant Proteins
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