LP44 (hydrochloride)
Product Specifications
UNSPSC Description
LP44 (hydrochloride) is a selective 5-HT7 agonist with Ki of 0.22 nM. LP44 (hydrochloride) induces hypothermic effect in a dose-dependent manner by intracerebroventricular injection. LP44 (hydrochloride) not causes considerable hypothermic response by intraperitoneal administration[1].
Target Antigen
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein;Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/lp44-hydrochloride.html
Purity
98.06
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(CCCCCN1CCN(C(C=CC=C2)=C2SC)CC1)NC3C4=CC=CC=C4CCC3.Cl
Molecular Weight
488.13
References & Citations
[1]Naumenko VS,et al. On the role of brain 5-HT7 receptor in the mechanism of hypothermia: comparison with hypothermia mediated via 5-HT1A and 5-HT3 receptor. Neuropharmacology. 2011 Dec;61(8):1360-5.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C (Powder, sealed storage, away from moisture)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-103101/LP44-hydrochloride-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-103101/LP44-hydrochloride-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
824958-12-5
Available Sizes
Curated Selection
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