Ondansetron
Ondansetron (GR 38032; SN 307) is a highly selective 5-HT3 receptor antagonist with an IC50 value of 103 pM. Ondansetron exerts its antiemetic effect by antagonizing 5-HT receptors located in localized neurons in the peripheral and central nervous systems. Ondansetron can inhibit nausea and vomiting induced by chemotherapy and radiotherapy[1][2][3][4][5][6][7][8].
Product Specifications
CAS Number
[99614-02-5]
Product Name Alternative
GR 38032; SN 307
UNSPSC
12352005
Hazard Statement
H301, H318
Target
5-HT Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/Ondansetron.html
Purity
99.46
Solubility
DMSO : 10 mg/mL (ultrasonic)
Smiles
O=C1C(CN2C=CN=C2C)CCC(N3C)=C1C4=C3C=CC=C4
Molecular Formula
C18H19N3O
Molecular Weight
293.36
Precautions
H301, H318
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
Launched
Isoform
Lactoferrin
Citation 01
Available Sizes
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