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NH-bis (C2-PEG2-NH-Boc)

NH-bis (C2-PEG2-NH-Boc) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Product Specifications

CAS Number

2182601-69-8

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

PROTAC Linkers

Type

Reference compound

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/nh-bis-c2-peg2-nh-boc.html

Purity

99.93

Solubility

10 mM in DMSO

Smiles

O=C(OC(C)(C)C)NCCOCCOCCNCCOCCOCCNC(OC(C)(C)C)=O

Molecular Formula

C22H45N3O8

Molecular Weight

479.61

Precautions

H302, H315, H319, H335

References & Citations

[1]An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

Alkyl/ether Linkers; PEG Linkers

Available Sizes

Frequently Asked Questions

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