EDDP (perchlorate)

EDDP perchlorate is an N-desmethyl metabolite of Methadone by intestinal, hepatic, and cytochrome P450 (CYP) 3A4[1].

Product Specifications

CAS Number

[31161-17-8]

UNSPSC

12352005

Hazard Statement

H301-H336

Target

Drug Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/eddp-perchlorate.html

Solubility

10 mM in DMSO

Smiles

O=Cl(=O)([O-])=O.C[N+](C(C1)C)=C(CC)C1(C2=CC=CC=C2)C3=CC=CC=C3

Molecular Formula

C20H24ClNO4

Molecular Weight

377.86

Precautions

P261-P264-P270-P271-P304+P340-P330-P403+P233-P405-P501

References & Citations

[1]Kharasch ED, et, al. Role of hepatic and intestinal cytochrome P450 3A and 2B6 in the metabolism, disposition, and miotic effects of methadone. Clin Pharmacol Ther. 2004 Sep;76 (3) :250-69. |[2]Fucci N, et, al. Simultaneous detection of some drugs of abuse in saliva samples by SPME technique. Forensic Sci Int. 2003 Jun 24;134 (1) :40-5.