Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-TIMP3 Antibody Picoband® (Cy3 Conjugate)

Boster Bio Anti-TIMP3 Antibody Picoband® catalog # A00477. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Metalloproteinase inhibitor 3 is a protein that in humans is encoded by the TIMP3 gene. It is mapped to 22q12.1-q13.2. This gene belongs to the tissue inhibitor of metalloproteinases gene family. The proteins encoded by this gene family are inhibitors of the matrix metalloproteinases, a group of peptidases involved in degradation of theextracellular matrix (ECM). Expression of this gene is induced in response to mitogenic stimulation and this netrin domain-containing protein is localized to the ECM. Mutations in this gene have been associated with the autosomal dominant disorder Sorsby's fundus dystrophy.

Synonyms

Metalloproteinase inhibitor 3;Protein MIG-5;Tissue inhibitor of metalloproteinases 3;TIMP-3;TIMP3;

Gene Name

Metalloproteinase inhibitor 3

UniProt

P35625

Host

Rabbit

Reactivity

Human,Mouse,Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

A synthetic peptide corresponding to a sequence in the middle region of human TIMP3, different from the related mouse and rat sequences by two amino acids.

Clonality

Polyclonal

Tissue Specificity

Ubiquitously expressed.

Applications

ELISA,WB

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15.

Storage Conditions

Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A00477

Product MSDS

https://www.bosterbio.com/msds?sku=A00477

Fragment

Rabbit IgG

Applications Notes

ELISA, 0.1-0.5μg/ml, -<br>Western blot, 0.1-0.5μg/ml, Mouse, Rat, Human<br>

Subcellular Location

Secreted, extracellular space, extracellular matrix.

Protein Name

Metalloproteinase inhibitor 3

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

ZKSCAN1 Rabbit pAb
MBS8559736-01 0.1 mL

ZKSCAN1 Rabbit pAb

Ask
View Details
ZKSCAN1 Rabbit pAb
MBS8559736-02 0.1 mL (AF405L)

ZKSCAN1 Rabbit pAb

Ask
View Details
ZKSCAN1 Rabbit pAb
MBS8559736-03 0.1 mL (AF405S)

ZKSCAN1 Rabbit pAb

Ask
View Details
ZKSCAN1 Rabbit pAb
MBS8559736-04 0.1 mL (AF610)

ZKSCAN1 Rabbit pAb

Ask
View Details
ZKSCAN1 Rabbit pAb
MBS8559736-05 0.1 mL (AF635)

ZKSCAN1 Rabbit pAb

Ask
View Details
ZKSCAN1 Rabbit pAb
MBS8559736-06 0.1 mL (APC)

ZKSCAN1 Rabbit pAb

Ask
View Details