Anti-Bonzo/CXCR6 Antibody Picoband® (Biotine Conjugate)

Boster Bio Anti-Bonzo/CXCR6 Antibody catalog # PA2082. Tested in IHC, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

CXCR6 (Chemokine,CXC Motif, Receptor 6), also known as STRL33, is a protein that in humans is encoded by the CXCR6 gene. By Southern blot analysis of genomic DNA and somatic cell hybrid analysis, Liao et al. (1997) mapped the single-copy STRL33 gene to chromosome 3. Matloubian et al. (2000) found that human and mouse cells expressing CXCR6 showed a strong chemotactic response to CXCL16 but not to other chemokines. The authors concluded that CXCL16 and CXCR6 probably function in interactions between dendritic cells and T cells and in regulating T-cell migration in the splenic red pulp. Kim et al. (2001) concluded that CXCR6 may be important in the trafficking of effector T cells mediating type-1 inflammation.

Synonyms

C-X-C chemokine receptor type 6;CXC-R6;CXCR-6;CDw186;G-protein coupled receptor STRL33;G-protein coupled receptor bonzo;CD186;CXCR6;BONZO, STRL33, TYMSTR;

Gene Name

C-X-C chemokine receptor type 6

UniProt

O00574

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the C-terminus of human Bonzo, different from the related mouse and rat sequences by three amino acids.

Clonality

Polyclonal

Tissue Specificity

Expressed in lymphoid tissues and activated T cells.

Applications

IHC,WB

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Receptor for the C-X-C chemokine CXCL16. Used as a coreceptor by SIVs and by strains of HIV-2 and m-tropic HIV-1.

Storage Conditions

Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.