Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-MCM3 Antibody Picoband® (Biotine Conjugate)

Boster Bio Anti-MCM3 Antibody catalog # PA1651. Tested in Flow Cytometry, IF, IHC, ICC, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

MCM3 (MINICHROMOSOME MAINTENANCE, S. CEREVISIAE, HOMOLOG OF, 3), also called RLFB or P1 PROTEIN, is a protein that in humans is encoded by the MCM3 gene. MCM3 is one of the highly conserved mini-chromosome maintenance proteins (MCM) that are involved in the initiation of eukaryotic genome replication. The MCM3 gene is mapped to 6p12.2. This protein is a subunit of the protein complex that consists of MCM2-7. It has been shown to interact ly with MCM5/CDC46. This protein also interacts with, and thus is acetlyated by MCM3AP, a chromatin-associated acetyltransferase. The acetylation of this protein inhibits the initiation of DNA replication and cell cycle progression.

Synonyms

DNA replication licensing factor MCM3;3.6.4.12;DNA polymerase alpha holoenzyme-associated protein P1;P1-MCM3;RLF subunit beta;p102;MCM3;

Gene Name

DNA replication licensing factor MCM3

UniProt

P25205

Host

Rabbit

Reactivity

Human,Mouse,Rat

Cross Reactivity

No cross-reactivity with other proteins

Immunogen

A synthetic peptide corresponding to a sequence at the N-terminus of human MCM3, identical to the related rat and mouse sequences.

Clonality

Polyclonal

Tissue Specificity

Heart, liver, duodenum, blood vessels and kidney.

Applications

Flow Cytometry,IF,IHC,ICC,WB

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for DNA replication and cell proliferation.

Storage Conditions

Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=PA1651

Product MSDS

https://www.bosterbio.com/msds?sku=PA1651

Fragment

Rabbit IgG

Applications Notes

Western blot, 0.1-0.5μg/ml, Human, Mouse, Rat<br> Immunohistochemistry (Paraffin-embedded Section), 0.5-1μg/ml, Human, Mouse, Rat, By Heat<br> Immunocytochemistry , 0.5-1μg/ml, Human, -<br> Immunocytochemistry/Immunofluorescence, 2μg/ml, Human<br> Flow Cytometry (Fixed), 1-3μg/1x10<sup>6</sup> cells, Human<br>

Subcellular Location

Nucleus.

Sequence Similarities

Belongs to the MCM family.

Protein Name

DNA replication licensing factor MCM3

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Chromosome 19 Open Reading Frame 53 (C19ORF53) Antibody (Biotin)
abx312241-01 20 µg

Chromosome 19 Open Reading Frame 53 (C19ORF53) Antibody (Biotin)

Ask
View Details
Chromosome 19 Open Reading Frame 53 (C19ORF53) Antibody (Biotin)
abx312241-02 50 µg

Chromosome 19 Open Reading Frame 53 (C19ORF53) Antibody (Biotin)

Ask
View Details
Chromosome 19 Open Reading Frame 53 (C19ORF53) Antibody (Biotin)
abx312241-03 100 µg

Chromosome 19 Open Reading Frame 53 (C19ORF53) Antibody (Biotin)

Ask
View Details
Chromosome 19 Open Reading Frame 53 (C19ORF53) Antibody (Biotin)
abx312241-04 200 µg

Chromosome 19 Open Reading Frame 53 (C19ORF53) Antibody (Biotin)

Ask
View Details
Chromosome 19 Open Reading Frame 53 (C19ORF53) Antibody (Biotin)
abx312241-05 1 mg

Chromosome 19 Open Reading Frame 53 (C19ORF53) Antibody (Biotin)

Ask
View Details
SODIUM PHOSPHATE, DIBASIC
S745-500G 500 g

SODIUM PHOSPHATE, DIBASIC

Ask
View Details