Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-Ribonuclease H2, subunit A/RNASEH2A Antibody Picoband® (Biotine Conjugate)

Boster Bio Anti-Ribonuclease H2, subunit A/RNASEH2A Antibody Picoband® catalog # A07386-2. Tested in ELISA, Flow Cytometry, WB applications. This antibody reacts with Human. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Ribonuclease H2 subunit A, also known as RNase H2 subunit A, is an enzyme that in humans is encoded by the RNASEH2A gene. The protein encoded by this gene is a component of the heterotrimeric type II ribonuclease H enzyme (RNAseH2). RNAseH2 is the major source of ribonuclease H activity in mammalian cells and endonucleolytically cleaves ribonucleotides. It is predicted to remove Okazaki fragment RNA primers during lagging strand DNA synthesis and to excise single ribonucleotides from DNA-DNA duplexes. Mutations in this gene cause Aicardi-Goutieres Syndrome (AGS), a an autosomal recessive neurological disorder characterized by progressive microcephaly and psychomotor retardation, intracranial calcifications, elevated levels of interferon-alpha and white blood cells in the cerebrospinal fluid.

Synonyms

Mucin-20; MUC-20; MUC20; KIAA1359; UNQ2782/PRO7170

Gene Name

mucin 20, cell surface associated

UniProt

O75792

Host

Rabbit

Reactivity

Human

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human Ribonuclease H2, subunit A/RNASEH2A recombinant protein (Position: R25-L299).

Clonality

Polyclonal

Tissue Specificity

Highly expressed in kidney, moderately in placenta, lung, prostate, liver, and digestive system. In the kidney, localized in the proximal tubules but not in the glomerulus or distal tubules. Detected in most of the male urogenital tract epithelia, with the exception of epididymis.

Applications

WB,Flow Cytometry,ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

May regulate MET signaling cascade. Seems to decrease hepatocyte growth factor (HGF)-induced transient MAPK activation. Blocks GRB2 recruitment to MET thus suppressing the GRB2-RAS pathway. Inhibits HGF-induced proliferation of MMP1 and MMP9 expression.

Storage Conditions

At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A07386-2

Product MSDS

https://www.bosterbio.com/msds?sku=A07386-2

Fragment

Rabbit IgG

Applications Notes

Western blot, 0.25-0.5 μg/ml, Human<br> Flow Cytometry (Fixed), 1-3 μg/1x10<sup>6</sup> cells, Human<br> ELISA, 0.1-0.5 μg/ml, -<br>

Subcellular Location

Apical cell membrane. Basolateral cell membrane. Microvillus membrane. Secreted.

Protein Name

Gamma-aminobutyric acid type B receptor subunit 1

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Recombinant Xenopus laevis Protein Wnt-7c (wnt7c)
MBS1174673-01 0.02 mg (E-Coli)

Recombinant Xenopus laevis Protein Wnt-7c (wnt7c)

Ask
View Details
Recombinant Xenopus laevis Protein Wnt-7c (wnt7c)
MBS1174673-02 0.1 mg (E-Coli)

Recombinant Xenopus laevis Protein Wnt-7c (wnt7c)

Ask
View Details
Recombinant Xenopus laevis Protein Wnt-7c (wnt7c)
MBS1174673-03 0.02 mg (Yeast)

Recombinant Xenopus laevis Protein Wnt-7c (wnt7c)

Ask
View Details
Recombinant Xenopus laevis Protein Wnt-7c (wnt7c)
MBS1174673-04 0.1 mg (Yeast)

Recombinant Xenopus laevis Protein Wnt-7c (wnt7c)

Ask
View Details
Recombinant Xenopus laevis Protein Wnt-7c (wnt7c)
MBS1174673-05 0.02 mg (Baculovirus)

Recombinant Xenopus laevis Protein Wnt-7c (wnt7c)

Ask
View Details
Recombinant Xenopus laevis Protein Wnt-7c (wnt7c)
MBS1174673-06 0.02 mg (Mammalian-Cell)

Recombinant Xenopus laevis Protein Wnt-7c (wnt7c)

Ask
View Details