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SKF 106760

SKF 106760 is a potent platelet fibrin receptor (glycoprotein IIb/IIIa) antagonist with significant antiplatelet and antithrombotic activities. SKF 106760 inhibits platelet aggregation in dogs in vitro and prevents thrombus formation in stenotic carotid arteries. SKF 106760 has also shown elimination effects against aspirin-resistant thrombi that develop in the setting of high-grade stenosis[1].

Product Specifications

CAS Number

126053-71-2

UNSPSC

12352209

Target

Endogenous Metabolite

Type

Peptides

Related Pathways

Metabolic Enzyme/Protease

Applications

Neuroscience-Neuromodulation

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/skf-106760.html

Smiles

N=C(N)NCCC[C@@H]1N(C([C@H](CSSC(C)([C@H](NC([C@@H](NC(CNC1=O)=O)CC(O)=O)=O)C(N)=O)C)NC(C)=O)=O)C

Molecular Formula

C23H39N9O8S2

Molecular Weight

633.74

References & Citations

[1]Antithrombotic effects of a platelet fibrinogen receptor antagonist in a canine model of carotid artery thrombosis

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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