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Anti-Drebrin/DBN1 Antibody Picoband® (monoclonal, 4F6E7) (Biotine Conjugate)

Boster Bio Anti-Drebrin/DBN1 Antibody Picoband® (monoclonal, 4F6E7) catalog # M05530-4. Tested in Flow Cytometry, IHC, WB applications. This antibody reacts with Human, Mouse, Rat, Monkey. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Drebrin is a protein that in humans is encoded by the DBN1 gene. The protein encoded by this gene is a cytoplasmic actin-binding protein thought to play a role in the process of neuronal growth. It is a member of the drebrin family of proteins that are developmentally regulated in the brain. A decrease in the amount of this protein in the brain has been implicated as a possible contributing factor in the pathogenesis of memory disturbance in Alzheimer's disease. At least two alternative splice variants encoding different protein isoforms have been described for this gene.

Synonyms

Cytochrome c oxidase subunit 4 isoform 1, mitochondrial; Cytochrome c oxidase polypeptide IV; Cytochrome c oxidase subunit IV isoform 1; COX IV-1; COX4I1; COX4

Gene Name

cytochrome c oxidase subunit 4I1

UniProt

Q16643

Host

Mouse

Reactivity

Human,Mouse,Rat,Monkey

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human Drebrin/DBN1 recombinant protein (Position: H9-D649).

Clonality

Monoclonal

Clone

Clone: 4F6E7

Tissue Specificity

Highly expressed in liver. Expressed in testis and weakly in colon.

Applications

WB,IHC,Flow Cytometry

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

This protein is one of the nuclear-coded polypeptide chains of cytochrome c oxidase, the terminal oxidase in mitochondrial electron transport.

Storage Conditions

At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=M05530-4

Product MSDS

https://www.bosterbio.com/msds?sku=M05530-4

Fragment

Mouse IgG2a

Applications Notes

Western blot, 0.25-0.5 μg/ml, Human, Mouse, Rat, Monkey<br> Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Human, Rat<br> Flow Cytometry (Fixed), 1-3 μg/1x10<sup>6</sup> cells, Human<br>

Subcellular Location

Cytoplasm.

Protein Name

RNA-binding protein Musashi homolog 1

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