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Anti-CD103/Itgae Antibody (Biotine Conjugate)

Boster Bio Anti-CD103/Itgae Antibody Picoband® catalog # A07091-2. Tested in ELISA, IHC applications. This antibody reacts with Mouse, Rat.

Product Specifications

Background

ITGAE(INTEGRIN, ALPHA-E), also known as CD103, is an integrin protein that in human is encoded by the ITGAE gene. The ITGAE gene is mapped to chromosome 17p13 by inclusion within a BAC contig. ITGAE is expressed widely on intraepithelial lymphocyte(IEL) T cells(both alphabeta T cells and gammadelta T cells) and on some peripheral regulatory T cells(Tregs) which is important for decreasing the immune response and appears to play a crucial role in the prevention of autoimmune diseases. ITGAE shares overall homology with other alpha integrins but has a unique 55-amino acid "extra" region located just N-terminal to the I domain that contains 18 consecutive charged residues and a proteolytic cleavage site.

Synonyms

Ribosome-binding protein 1; 180 kDa ribosome receptor homolog; RRp; ES/130-related protein; Ribosome receptor protein; RRBP1; KIAA1398

Gene Name

ribosome binding protein 1

UniProt

Q60677

Host

Rabbit

Reactivity

Mouse,Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived mouse CD103/Itgae recombinant protein (Position: F20-E1061).

Clonality

Polyclonal

Tissue Specificity

Expressed in kidney.

Applications

IHC,ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Acts as a ribosome receptor and mediates interaction between the ribosome and the endoplasmic reticulum membrane.

Storage Conditions

At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A07091-2

Product MSDS

https://www.bosterbio.com/msds?sku=A07091-2

Fragment

Rabbit IgG

Applications Notes

Immunohistochemistry(Paraffin-embedded Section), 2-5 μg/ml, Mouse, Rat<br> ELISA, 0.1-0.5 μg/ml, -<br>

Subcellular Location

Endoplasmic reticulum membrane, Single-pass type III membrane protein.

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