Welcome to GenPrice! Check out our latest updates.

Shopping Cart (0)

Your cart is empty

Add some products to get started!

Anti-GNAO1 Antibody Picoband® (Biotine Conjugate)

Boster Bio Anti-GNAO1 Antibody Picoband® catalog # A05532-2. Tested in ELISA, WB applications. This antibody reacts with Human, Mouse, Rat. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Guanine nucleotide-binding protein G(o) subunit alpha is a protein that in humans is encoded by the GNAO1 gene. The protein encoded by this gene represents the alpha subunit of the Go heterotrimeric G-protein signal-transducing complex. Defects in this gene are a cause of early-onset epileptic encephalopathy. Two transcript variants encoding different isoforms have been found for this gene.

Synonyms

Spermine oxidase; Polyamine oxidase 1; PAO-1; PAOh1; Smox; Smo

Gene Name

spermine oxidase

UniProt

P09471

Host

Rabbit

Reactivity

Human,Mouse,Rat

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human GNAO1 recombinant protein (Position: M1-R179).

Clonality

Polyclonal

Tissue Specificity

Widely expressed. Isoform 1 and isoform 2 are expressed at higher level in brain and skeletal muscle. Isoform 7 is found in brain and spleen, isoform 10 is widely expressed but found at lower level in heart, kidney, liver and lung.

Applications

WB,ELISA

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Function

Flavoenzyme which catalyzes the oxidation of spermine to spermidine. Can also use N1-acetylspermine and spermidine as substrates, with different affinity depending on the isoform (isozyme) and on the experimental conditions. Plays an important role in the regulation of polyamine intracellular concentration and has the potential to act as a determinant of cellular sensitivity to the antitumor polyamine analogs. May contribute to beta-alanine production via aldehyde dehydrogenase conversion of 3-amino-propanal.

Storage Conditions

At -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freezing and thawing.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A05532-2

Product MSDS

https://www.bosterbio.com/msds?sku=A05532-2

Fragment

Rabbit IgG

Applications Notes

Western blot, 0.1-0.25 μg/ml, Mouse, Rat<br> ELISA, 0.1-0.5 μg/ml, -<br>

Subcellular Location

Cytoplasm. Nucleus. Cytoplasm.

Protein Name

Serine protease HTRA3

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

Imidaprilate
T11642-01 10mg

Imidaprilate

Ask
View Details
Imidaprilate
T11642-02 1g

Imidaprilate

Ask
View Details
Imidaprilate
T11642-03 1mg

Imidaprilate

Ask
View Details
Imidaprilate
T11642-04 50mg

Imidaprilate

Ask
View Details
Imidaprilate
T11642-05 5mg

Imidaprilate

Ask
View Details
BMPR1B Antibody
A46303-100UG 100 µg

BMPR1B Antibody

Ask
View Details