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Anti-SUZ12 Antibody Picoband® (Biotine Conjugate)

Boster Bio Anti-SUZ12 Antibody Picoband® catalog # A00583-1. Tested in ELISA, IHC, ICC, WB applications. This antibody reacts with Human, Mouse. The brand Picoband indicates this is a premium antibody that guarantees superior quality, high affinity, and strong signals with minimal background in Western blot applications. Only our best-performing antibodies are designated as Picoband, ensuring unmatched performance.

Product Specifications

Background

Polycomb protein SUZ12 is a protein that in humans is encoded by the SUZ12 gene. It is mapped to 17q11.2. This zinc finger gene has been identified at the breakpoints of a recurrent chromosomal translocation reported in endometrial stromal sarcoma. Recombination of these breakpoints results in the fusion of this gene and JAZF1. The protein encoded by this gene contains a zinc finger domain in the C terminus of the coding region.

Synonyms

Polycomb protein SUZ12; Chromatin precipitated E2F target 9 protein ChET 9 protein; Joined to JAZF1 protein; Suppressor of zeste 12 protein homolog; SUZ12; CHET9, JJAZ1, KIAA0160

Gene Name

SUZ12 polycomb repressive complex 2 subunit

UniProt

Q15022

Host

Rabbit

Reactivity

Human,Mouse

Cross Reactivity

No cross-reactivity with other proteins.

Immunogen

E.coli-derived human SUZ12 recombinant protein (Position: K72-K483).

Clonality

Polyclonal

Tissue Specificity

Overexpressed in breast and colon cancer.

Applications

ELISA,IHC,ICC,WB

Purification

Immunogen affinity purified.

Concentration

Adding 0.2 ml of distilled water will yield a concentration of 500 μg/ml.

Form

Lyophilized

Reconstitution

Add 0.2ml of distilled water will yield a concentration of 500ug/ml.

Function

Polycomb group (PcG) protein. Component of the PRC2/EED-EZH2 complex, which methylates 'Lys-9' (H3K9me) and 'Lys-27' (H3K27me) of histone H3, leading to transcriptional repression of the affected target gene. The PRC2/EED-EZH2 complex may also serve as a recruiting platform for DNA methyltransferases, thereby linking two epigenetic repression systems. Genes repressed by the PRC2/EED-EZH2 complex include HOXC8, HOXA9, MYT1 and CDKN2A.

Storage Conditions

Store at -20℃ for one year from date of receipt. After reconstitution, at 4℃ for one month. It can also be aliquotted and stored frozen at -20℃ for six months. Avoid repeated freeze-thaw cycles.

Product Datasheet

https://www.bosterbio.com/datasheet?sku=A00583-1

Product MSDS

https://www.bosterbio.com/msds?sku=A00583-1

Fragment

Rabbit IgG

Applications Notes

Western blot, 0.25-0.5 μg/ml, Human<br> Immunohistochemistry(Paraffin-embedded Section), 0.5-1 μg/ml, Mouse, By Heat<br> Immunocytochemistry, 0.5-1 μg/ml, Human<br> ELISA, 0.1-0.5 μg/ml, -<br>
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