Glochidiol
Glochidiol is an orally active tubulin polymerization inhibitor with an IC50 of 2.76 μM. Glochidiol shows anti-cancer activity[1].
Product Specifications
CAS Number
6610-56-6
UNSPSC
12352211
Target
Microtubule/Tubulin
Type
Natural Products
Related Pathways
Cell Cycle/DNA Damage; Cytoskeleton
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/glochidiol.html
Solubility
10 mM in DMSO
Smiles
C[C@]12[C@@](CC[C@@]3([H])[C@]2(CC[C@]4(C)[C@]3([H])[C@@H](CC4)C(C)=C)C)([H])[C@@]5([C@@](C(C)([C@H](O)C[C@H]5O)C)([H])CC1)C
Molecular Formula
C30H50O2
Molecular Weight
442.72
References & Citations
[1]Chen H, et al. Glochidiol, a natural triterpenoid, exerts its anti-cancer effects by targeting the colchicine binding site of tubulin. Invest New Drugs. 2021 Apr;39 (2) :578-586.
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
Frequently Asked Questions
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