IDO2-IN-1
IDO2-IN-1 is an orally active and potent Indoleamine 2,3-dioxygenase 2 (IDO2) inhibitor with an IC50 value of 112 nM. IDO2-IN-1 can be used for inflammatory autoimmunity research[1].
Product Specifications
CAS Number
[2803768-09-2]
UNSPSC
12352005
Target
Indoleamine 2,3-Dioxygenase (IDO)
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ido2-in-1.html
Purity
98.10
Solubility
DMSO : 140 mg/mL (ultrasonic)
Smiles
BrC1=CC=CC(CN/C(C2=NON=C2NCCN3C=C(N=N3)CNC(C4=NC=CC=C4)=O)=N\O)=C1
Molecular Formula
C21H21BrN10O3
Molecular Weight
541.36
References & Citations
[1]He G, et al. Discovery of the First Selective IDO2 Inhibitor As Novel Immunotherapeutic Avenues for Rheumatoid Arthritis. J Med Chem. 2022 Aug 11.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, sealed storage, away from moisture and light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IDO1; IDO2
Available Sizes
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