JAK1-IN-8

JAK1-IN-8, a potent JAK1 inhibitor (IC50[1].

Product Specifications

CAS Number

[1973485-18-5]

UNSPSC

12352005

Target

JAK

Type

Reference compound

Related Pathways

Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/jak1-in-8.html

Purity

95.0

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(C1CC1)NC2=CN3C(C4=CC(F)=C(CN5CCS(=O)(CC5)=O)C=C4)=CC=CC3=N2

Molecular Formula

C22H23FN4O3S

Molecular Weight

442.51

References & Citations

[1]Jin Li, et al. Composés d'imidazo[1,2-a]pyridin-2-ylamine substitués, compositions pharmaceutiques et leurs méthodes d'utilisation. Patent WO2016119700A1.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

JAK1; JAK2; JAK3

Available Sizes

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