JAK1-IN-8
JAK1-IN-8, a potent JAK1 inhibitor (IC50[1].
Product Specifications
CAS Number
[1973485-18-5]
UNSPSC
12352005
Target
JAK
Type
Reference compound
Related Pathways
Epigenetics; JAK/STAT Signaling; Protein Tyrosine Kinase/RTK; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/jak1-in-8.html
Purity
95.0
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(C1CC1)NC2=CN3C(C4=CC(F)=C(CN5CCS(=O)(CC5)=O)C=C4)=CC=CC3=N2
Molecular Formula
C22H23FN4O3S
Molecular Weight
442.51
References & Citations
[1]Jin Li, et al. Composés d'imidazo[1,2-a]pyridin-2-ylamine substitués, compositions pharmaceutiques et leurs méthodes d'utilisation. Patent WO2016119700A1.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
JAK1; JAK2; JAK3
Available Sizes
Curated Selection
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