NP-313
Product Specifications
UNSPSC Description
NP-313 is a potent antithrombotic agent that inhibits platelet aggregation and activation. NP-313 has dual inhibition of thromboxane A 2 synthesis and selective inhibition of SOCC-mediated Ca2+ inward flow[1].
Target Antigen
Thrombin
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/np-313.html
Purity
99.58
Solubility
DMSO : 25 mg/mL (ultrasonic)
Smiles
CC(NC(C1=O)=C(Cl)C(C2=C1C=CC=C2)=O)=O
Molecular Weight
249.65
References & Citations
[1]Heng-Lan Kuo, et al. NP-313, 2-acetylamino-3-chloro-1,4-naphthoquinone, a novel antithrombotic agent with dual inhibition of thromboxane A(2) synthesis and calcium entry. Br J Pharmacol. 2011 Apr;162(8):1871-83.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-129496/NP-313-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-129496/NP-313-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
5397-78-4
Available Sizes
Curated Selection
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