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NP-313

Product Specifications

UNSPSC Description

NP-313 is a potent antithrombotic agent that inhibits platelet aggregation and activation. NP-313 has dual inhibition of thromboxane A 2 synthesis and selective inhibition of SOCC-mediated Ca2+ inward flow[1].

Target Antigen

Thrombin

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/np-313.html

Purity

99.58

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

CC(NC(C1=O)=C(Cl)C(C2=C1C=CC=C2)=O)=O

Molecular Weight

249.65

References & Citations

[1]Heng-Lan Kuo, et al. NP-313, 2-acetylamino-3-chloro-1,4-naphthoquinone, a novel antithrombotic agent with dual inhibition of thromboxane A(2) synthesis and calcium entry. Br J Pharmacol. 2011 Apr;162(8):1871-83.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-129496/NP-313-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-129496/NP-313-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

5397-78-4

Available Sizes

Curated Selection

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