What is the catalog number for Recombinant Mouse IL18BP?

The catalog number for Recombinant Mouse IL18BP is Z200429.

What sizes are available for Recombinant Mouse IL18BP?

Recombinant Mouse IL18BP is available in the following size(s): 1 mg.

Is Recombinant Mouse IL18BP in stock?

Recombinant Mouse IL18BP is currently made to order / not held in immediate stock. Contact us for lead time.

Recombinant Mouse IL18BP

IL-18BP is a secreted protein that binds IL-18 with high affinity and prevents its interaction with the IL-18R. Different isoforms of IL-18BP have been demonstrated, four in human and two in the murine system, and biological activity is limited to particular isoforms. IL-18 binding protein (IL-18BP) is a constitutively expressed and secreted protein that resembles the extracellular domains of Ig-like receptors but has no transmembrane form. Because IL-18 is one of the early signals leading to IFN-gamma production by Th1 cells, blocking IL-18 activity by IL-18BP may be involved in down-modulation of the early phases of immune responses.

Product Specifications

Gene Name

IL18BP

Gene Aliases

IL-18BP, Interferon gamma-inducing factor-binding protein<br/>Recombinant Mouse Interleukin-18 Binding Protein (IL18BP)

Gene ID

16068

Accession Number

Q9Z0M9

Organism

Mouse

Source

E. coli

Concentration

<1.0 EU/μg of recombinant protein as determined by the LAL method.

Purity

>95% as determined by SDS-PAGE

Solubility

A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

Function

The activity of recombinant Interleukin-18 Binding Protein was determined by the ability to bind IL-18 in functional ELISA.

Molecular Weight

19

Shipping Conditions

Ambient Temperature

Storage Conditions

Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.