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Recombinant Human TNFRSF1A

A member of the TNFR superfamily, it is one of the major receptors for tumor necrosis factor-alpha (TNFα). Binding of either TNF-α or TNF-β to TNFRSF1A starts a signal transduction pathway that results in the activation of the transduction factor NF-κB, whose target genes are involved in the regulation of inflammatory responses, and, in certain cells induce apoptosis.

Product Specifications

Gene Name

TNFRSF1A

Gene Aliases

Soluble Tumor Necrosis Factor Type I, TNFRSF1A, TNFAR, TNF-R55, TNFR60, p55, CD120a

Gene ID

7132

Accession Number

P19438

Organism

Human

Source

E. coli

Concentration

<1.0 EU/μg of recombinant protein as determined by the LAL method

Purity

>95% as determined by SDS-PAGE

Solubility

A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers.

Molecular Weight

18.4

Shipping Conditions

Ambient Temperature

Storage Conditions

The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° - 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles.

Appearance

Lyophilized Powder

Formulation

coming soon

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