Recombinant Human NOV
Protein NOV homolog is a secreted, regulatory protein found mainly in muscle and nervous tissue which interacts with many molecules, including fibulin 1C, CCN2, Connexin43 (to regulate the suppression of cell proliferation) and S100A4 (trigger activation of calcium channels). By signalling through an integrin pathway, NovH promotes both cell migration and adhesion. Increased levels of NovH have been found in some tumour cells and in most nephroblastomas while decreased levels of this protein may also promote tumour growth.
Product Specifications
Gene Name
NOV
Gene Aliases
Gene ID
4856
Accession Number
P48745
Organism
Human
Source
E. coli
Concentration
<1.0 EU/μg of recombinant protein as determined by the LAL method.
Purity
>95% as determined by SDS-PAGE
Solubility
Reconstitute at 250 μg/mL in sterile PBS
Function
Measured by its ability to mediate Balb/3T3 mouse embryonic fibroblast cell adhesion
Molecular Weight
36.5
Shipping Conditions
Ambient Temperature
Storage Conditions
Appearance
Lyophilized Powder
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS
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