Clematomandshurica saponin B
Clematomandshurica saponins B shows significant inhibitory activity on cyclooxygenase-2 (IC50=2.58 mM) [1].
Product Specifications
UNSPSC
12352005
Target
COX
Type
Natural Products
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/clematomandshurica-saponin-b.html
Solubility
10 mM in DMSO
Smiles
OC[C@H]([C@H]([C@@H]([C@H]1O)O)O[C@H]2[C@@H]([C@@H]([C@H]([C@@H](O2)C)O)O)O)O[C@H]1OC[C@H]([C@H]([C@@H]([C@H]3O)O)O)O[C@H]3OC([C@]45[C@](CC(C)(CC5)C)([H])C6=CC[C@@]([C@@]7([C@@](C(C)([C@H](CC7)O[C@H]8[C@@H]([C@H]([C@H](CO8)O)O)O[C@H]9[C@@H]([C@@H]([C@H]([C@@H](O9)C)O)O[C@H]%10[C@@H]([C@@H]([C@@H](CO%10)O[C@@H]%11O[C@@H]([C@H]([C@@H]([C@H]%11O)O)O[C@H]%12[C@@H]([C@H]([C@@H]([C@H](O%12)CO[C@H]%13[C@@H]([C@@H]([C@H]([C@@H](O%13)C)O)O)O)O)O)OC(/C=C/C%14=CC(O)=C(C=C%14)OC)=O)CO)O)O)O)C)([H])CC%15)C)([H])[C@]%15(C)[C@@]6(CC4)C)=O
Molecular Formula
C92H142O46
Molecular Weight
1984.08
References & Citations
[1]Shi S, Jiang D, Dong C, Tu P. Triterpene saponins from clematis mandshurica. J Nat Prod. 2006;69 (11) :1591-1595.
Shipping Conditions
Room temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-N4230/Clematomandshurica-saponin-B-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-N4230/
Scientific Category
Natural Products
Clinical Information
No Development Reported
Isoform
COX-2
CAS Number
[916649-91-7]
Available Sizes
Curated Selection
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