Human FGF-12 (Fibroblast Growth Factor-12)

<strong>Human FGF-12 (Fibroblast Growth Factor-12)</strong>_x000D_ <strong>Catalog number:</strong> B2018635_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Amount:</strong> 1 ug_x000D_ <strong>Molecular Weight or Concentration:</strong> ~20 kDa_x000D_ <strong>Supplied as:</strong> Powder_x000D_ <strong>Applications:</strong> a molecular tool for various biochemical applications_x000D_ <strong>Storage:</strong> -20°C_x000D_ <strong>Keywords:</strong> FGF-12, Fibroblast growth factor 12_x000D_ <strong>Grade:</strong> Biotechnology grade. All products are highly pure. All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Wu D, Zhang P, Ma J, Xu J, Yang L, Xu W, Que H, Chen M, Xu H. Serum biomarker panels for the diagnosis of gastric cancer Cancer Med. 2019 Apr;8(4):1576-1583._x000D_ 2: Biadun M, Karelus R, Krowarsch D, Opalinski L, Zakrzewska M. FGF12: biology and function Differentiation. 2024 Sep-Oct;139:100740._x000D_ 3: Gao X, Liao Z, Su R, Zheng D, Huang G, Huang Z, Cheng X. Depletion of Fibroblast Growth Factor 12 Restrains the Viability, Stemness, and Motility of Colorectal Cancer Biomed Res Int. 2022 Jul 11;2022:9948461._x000D_ 4: Song SH, Kim K, Jo EK, Kim YW, Kwon JS, Bae SS, Sung JH, Park SG, Kim JT, Suh W. Fibroblast Growth Factor 12 Is a Novel Regulator of Vascular Smooth Muscle Cell Plasticity and Fate Arterioscler Thromb Vasc Biol. 2016 Sep;36(9):1928-36._x000D_ 5: Nakayama F, Yasuda T, Umeda S, Asada M, Imamura T, Meineke V, Akashi M. Fibroblast growth factor-12 (FGF12) translocation into intestinal epithelial cells is dependent on a novel cell-penetrating peptide domain: involvement of internalization in the in vivo role of exogenous FGF12 J Biol Chem. 2011 Jul 22;286(29):25823-34._x000D_ 6: Wildburger NC, Ali SR, Hsu WC, Shavkunov AS, Nenov MN, Lichti CF, LeDuc RD, Mostovenko E, Panova-Elektronova NI, Emmett MR, Nilsson CL, Laezza F. Quantitative proteomics reveals protein-protein interactions with fibroblast growth factor 12 as a component of the voltage-gated sodium channel 1.2 (nav1.2) macromolecular complex in Mammalian brain Mol Cell Proteomics. 2015 May;14(5):1288-300._x000D_ 7: Merhi Z, Polotsky AJ, Bradford AP, Buyuk E, Chosich J, Phang T, Jindal S, Santoro N. Adiposity Alters Genes Important in Inflammation and Cell Cycle Division in Human Cumulus Granulosa Cell Reprod Sci. 2015 Oct;22(10):1220-8._x000D_ 8: Zhu GJ, Liu F, Xu YG, Zhao CX, Zhao JG, Sun C. HMGN5 promotes invasion and migration of colorectal cancer through activating FGF/FGFR pathway Eur Rev Med Pharmacol Sci. 2021 Feb;25(3):1330-1338._x000D_ 9: Liu JF, Crépin M, Liu JM, Barritault D, Ledoux D. FGF-2 and TPA induce matrix metalloproteinase-9 secretion in MCF-7 cells through PKC activation of the Ras/ERK pathway Biochem Biophys Res Commun. 2002 May 17;293(4):1174-82._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/8852763">10: Meddahi A, Lemdjabar H, Caruelle JP, Barritault D, Hornebeck W. FGF protection and inhibition of human neutrophil elastase by carboxymethyl benzylamide sulfonate dextran derivatives Int J Biol Macromol. 1996 Feb;18(1-2):141-5. </a>_x000D_ _x000D_ <strong>Products Related to Human FGF-12 (Fibroblast Growth Factor-12) can be found at</strong> <a href="https://moleculardepot.com/product-category/Proteins/"> Proteins</a>