RG-101 (sodium)

RG-101 sodium is a hepatocyte targeted N-acetylgalactosamine conjugated oligonucleotide that antagonises miR-122. miR-122 is an important host factor for hepatitis C virus (HCV) replication[1].

Product Specifications

Product Name Alternative

Temavirsen (sodium)

UNSPSC

12352208

Target

HCV; MicroRNA

Type

Oligonucleotides

Related Pathways

Anti-infection; Epigenetics

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/rg-101-sodium.html

Purity

95.38

Solubility

H2O : 100 mg/mL (ultrasonic)

Smiles

[RG-101(sodium)]

Molecular Formula

C295H410N78Na19O146P19S17

Molecular Weight

8537.6 (free acid)

References & Citations

[1]Meike H van der Ree, et al. Safety, tolerability, and antiviral effect of RG-101 in patients with chronic hepatitis C: a phase 1B, double-blind, randomised controlled trial. Lancet. 2017 Feb 18;389 (10070) :709-717.