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STING-IN-2

STING-IN-2 (C-170) is a potent and covalent STING inhibitor. STING-IN-2 efficiently inhibits both mouse STING (mmSTING) and human STING (hsSTING) . STING-IN-2 can be used for autoinflammatory disease research[1].

Product Specifications

CAS Number

346691-38-1

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

STING

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/sting-in-2.html

Purity

99.71

Solubility

DMSO : 125 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=C([N+]([O-])=O)O1)NC2=CC=C(CCCC)C=C2

Molecular Formula

C15H16N2O4

Molecular Weight

288.30

Precautions

H302, H315, H319, H335

References & Citations

[1]Simone M Haag, et al. Targeting STING with covalent small-molecule inhibitors. Nature. 2018 Jul;559 (7713) :269-273.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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