STING-IN-2
STING-IN-2 (C-170) is a potent and covalent STING inhibitor. STING-IN-2 efficiently inhibits both mouse STING (mmSTING) and human STING (hsSTING) . STING-IN-2 can be used for autoinflammatory disease research[1].
Product Specifications
CAS Number
[346691-38-1]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
STING
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/sting-in-2.html
Purity
99.71
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C([N+]([O-])=O)O1)NC2=CC=C(CCCC)C=C2
Molecular Formula
C15H16N2O4
Molecular Weight
288.30
Precautions
H302, H315, H319, H335
References & Citations
[1]Simone M Haag, et al. Targeting STING with covalent small-molecule inhibitors. Nature. 2018 Jul;559 (7713) :269-273.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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