N-Arachidonoyl-L-alanine

N-Arachidonoyl-L-alanine is an endocannabinoid analog with anti-cancer effects. N- Arachidonoyl-L-alanine kills HNSCC cells through 5-LO-mediated ROS productio[1].

Product Specifications

CAS Number

[401941-73-9]

Product Name Alternative

NALA

UNSPSC

12352209

Hazard Statement

H225, H350

Target

Reactive Oxygen Species (ROS)

Type

Peptides

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/n-arachidonoyl-l-alanine.html

Concentration

26.63 mM * 500 μL in Ethanol

Purity

99.0

Solubility

10 mM in DMSO

Smiles

C[C@@H](C(O)=O)NC(CCC/C=C\C/C=C\C/C=C\C/C=C\CCCCC)=O

Molecular Formula

C23H37NO3

Molecular Weight

375.54

Precautions

H225, H350

References & Citations

[1]Seok-Woo Park, et al. 5-lipoxygenase mediates docosahexaenoyl ethanolamide and N-arachidonoyl-L-alanine-induced reactive oxygen species production and inhibition of proliferation of head and neck squamous cell carcinoma cells. BMC Cancer. 2016 Jul 13:16:458.