Amino-PEG7-t-butyl ester
Amino-PEG7-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Amino-PEG7-t-butyl ester is a PEG reagent containing an amino NH2 group with a t-butyl protected carboxyl group (Boc) . Amino-PEG7-t-butyl ester can be used in drug delivery research[2].
Product Specifications
CAS Number
[2428400-07-9]
UNSPSC
12352211
Hazard Statement
H315, H319, H335
Target
Biochemical Assay Reagents; PROTAC Linkers
Type
Reference compound
Related Pathways
Others; PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/amino-peg7-t-butyl-ester.html
Purity
99.84
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O=C(OC(C)(C)C)CCOCCOCCOCCOCCOCCOCCOCCN
Molecular Formula
C21H43NO9
Molecular Weight
453.57
Precautions
H315, H319, H335
References & Citations
[1]Rosario Pignatello, et al. New Amphiphilic Conjugates of Amino–Poly (ethylene glycols) With Lipoamino Acids as Surface Modifiers of Colloidal Drug Carriers. Macromolecular Chemistry and Physics. 15 November 2012.|[2]Li H, et al. Discovery of Pentacyclic Triterpenoid PROTACs as a Class of Effective Hemagglutinin Protein Degraders. J Med Chem. 2022 May 26;65 (10) :7154-7169.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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