Amino-PEG7-t-butyl ester

Amino-PEG7-t-butyl ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Amino-PEG7-t-butyl ester is a PEG reagent containing an amino NH2 group with a t-butyl protected carboxyl group (Boc) . Amino-PEG7-t-butyl ester can be used in drug delivery research[2].

Product Specifications

CAS Number

[2428400-07-9]

UNSPSC

12352211

Hazard Statement

H315, H319, H335

Target

Biochemical Assay Reagents; PROTAC Linkers

Type

Reference compound

Related Pathways

Others; PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/amino-peg7-t-butyl-ester.html

Purity

99.84

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C(OC(C)(C)C)CCOCCOCCOCCOCCOCCOCCOCCN

Molecular Formula

C21H43NO9

Molecular Weight

453.57

Precautions

H315, H319, H335

References & Citations

[1]Rosario Pignatello, et al. New Amphiphilic Conjugates of Amino–Poly (ethylene glycols) With Lipoamino Acids as Surface Modifiers of Colloidal Drug Carriers. Macromolecular Chemistry and Physics. 15 November 2012.|[2]Li H, et al. Discovery of Pentacyclic Triterpenoid PROTACs as a Class of Effective Hemagglutinin Protein Degraders. J Med Chem. 2022 May 26;65 (10) :7154-7169.