(±) 8-HDHA

(±) 8-HDHA is an autoxidation product of docosahexaenoic acid (DHA) in vitro. It is also produced from incubations of DHA in rat liver, brain, and intestinal microsomes. (±) 8-HDHA is a potential marker of oxidative stress in brain and retina where DHA is an abundant polyunsaturated fatty acid.

Product Specifications

CAS Number

[90780-54-4]

Product Name Alternative

(±) 8-HDoHE; 8-hydroxy Docosahexaenoic acid; (±) 8-HDoHE

UNSPSC

12352211

Hazard Statement

H302, H315, H319, H335

Target

Endogenous Metabolite

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Assay Protocol

https://www.medchemexpress.com/racemic-8-hdha.html

Concentration

290.28 μM * 500 μL in Ethanol

Purity

99.9

Smiles

CC/C=C\C/C=C\C/C=C\C/C=C\CC(O)/C=C/C=C\CCC(O)=O

Molecular Formula

C22H32O3

Molecular Weight

344.49

Precautions

H302, H315, H319, H335

References & Citations

[1]VanRollins, et al. Autooxidation of docosahexaenoic acid: Analysis of ten isomers of hydroxydocosahexaenoate. J. Lipid Res. 25 (5), 507-517 (1984) .