R-30-Hydroxygambogic acid
R-30-Hydroxygambogic acid is polyprenylated xanthone epimer that can be isolated from gamboges of Garcinia hanburyi. R-30-Hydroxygambogic acid shows cytotoxicities to Human Leukemia K562 cell lines of IC50 values of 2.89 and 1.27 μM for K562/R and K562/S, respectively. R-30-Hydroxygambogic acid can be used for the research of cancer[1].
Product Specifications
CAS Number
[881027-35-6]
UNSPSC
12352005
Target
Others
Type
Natural Products
Related Pathways
Others
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/r-30-hydroxygambogic-acid.html
Purity
97.07
Solubility
10 mM in DMSO
Smiles
OC(/C(CO)=C\C[C@@]12[C@]34C(C(C5=C(O)C(C=C[C@](C)(O6)CC/C=C(C)/C)=C6C(C/C=C(C)\C)=C5O3)=O)=CC(C[C@@]4([H])C(C)(O2)C)([H])C1=O)=O
Molecular Formula
C38H44O9
Molecular Weight
644.75
References & Citations
[1]Han QB, et al. A pair of novel cytotoxic polyprenylated xanthone epimers from gamboges. Chem Biodivers. 2006 Jan;3 (1) :101-5.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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