Biotinylated Monoclonal Anti-FMC63 Antibody, Mouse IgG1, Avitag™ (Y45)
Monoclonal Anti-FMC63 Antibody, Mouse IgG1, Avitag™ (Y45) is a neutralizing mouse monoclonal antibody recombinantly expressed from human 293 cells (HEK293) . Biotinylation of this antibody is performed using Avitag™ technology. Briefly, the single lysine residue in the Avitag is enzymatically labeled with biotin.
Product Specifications
Background
FMC63 is an IgG2a mouse monoclonal antibody specific for CD19, which is a target for the immunotherapy of B lineage leukaemias and lymphomas. FMC63 scFv is the most commonly used ectodomain component of CD19-specific CARs. So far, most of reported CART19 trials contain the anti-CD19 scFv derived from FMC63, including the two FDA-approved CARs Kymriah and Yescarta.
CAS Number
9007-83-4
Host
HEK293
Origin Species
Mouse
Target
FMC63
Conjugation
Biotin-labeled
Tag
Mouse IgG1 & C-Avi | kappa
Applications
Flow Cytometry (Evaluation of Anti-CD19 (FMC63 scFv) CAR Expression) .
Stability
-20°C to -70°C for 24 months in lyophilized state; -70°C for 12 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please avoid repeated freeze-thaw cycles.
Format
Powder
Buffer
PBS, 0.5% BSA, pH7.4
Additives
Trehalose
Additionnal Information
Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
25tests*1
Host or Source
HEK293
Species
Mouse
Preservative
Trehalose
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