Monoclonal Anti-FMC63 Antibody, Mouse IgG1 (Y45) (HEK293)
Monoclonal Anti-FMC63 Antibody, Mouse IgG1 (Y45) (HEK293) is a neutralizing mouse monoclonal antibody recombinantly expressed from human 293 cells (HEK293), which provides higher batch consistency and long term security of supply.
Product Specifications
Background
FMC63 is an IgG2a mouse monoclonal antibody specific for CD19, which is a target for the immunotherapy of B lineage leukaemias and lymphomas. FMC63 scFv is the most commonly used ectodomain component of CD19-specific CARs. So far, most of reported CART19 trials contain the anti-CD19 scFv derived from FMC63, including the two FDA-approved CARs Kymriah and Yescarta.
Host
HEK293
Origin Species
Mouse
Target
FMC63
Conjugation
Unconjugated
Tag
Mouse IgG1 | Mouse Kappa
Applications
Flow Cytometry (Evaluation of Anti-CD19 (FMC63 scFv) CAR Expression) .
Stability
● -20°C to -70°C for 24 months in lyophilized state; ● -70°C for 12 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please avoid repeated freeze-thaw cycles.
Format
Powder
Buffer
PBS, 0.5% BSA, pH7.4
Additives
Trehalose
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
25tests*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/FM3-Y45P1.pdf
Species
Mouse
CAS Number
9007-83-4
Curated Selection
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