Human CTGF / CCN2 Protein, Tag Free
Human CTGF Protein, Tag Free (CTF-H5113) is expressed from E. coli cells. It contains AA Gly 253 - Ala 349 (Accession # Q5M8T4-1 ).
Product Specifications
Background
Connective Tissue Growth Factor (CTGF), also known as CCN2, is a member of the CCN (CCN1-6) family of modular matricellular proteins. Like other CCN proteins, mature human CTGF consists of IGF-binding protein domain, a vWF-C domain, a TSP-1 domain, and a cysteine knot heparin-binding domain. CTGF promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. Analysis of CCN2 function in vivo has focused primarily on its key role as a mediator of excess ECM synthesis in multiple fibrotic diseases.
Specifications
This protein carries no "tag". The protein has a calculated MW of 11.2 kDa. The protein migrates as 10-11 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE).
Expression Region
Gly 253 - Ala 349
Host
E. coli
Target
CTGF
Conjugation
Unconjugated
Tag
Native
Source
Human
Stability
The product MUST be stored at -70°C or lower upon receipt; -70°C for 3 months under sterile conditions.
Endotoxin
0.1 EU per μg
Purity
95%
Format
Liquid
Buffer
PBS, pH7.4
Additives
Glycerol
Molecular Weight
11.2 kDa
Shipping Conditions
Dry ice
Storage Conditions
-70°C
Documents
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
