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Human PAR2 Full Length Protein (VLP)

This gene encodes a member of the G-protein coupled receptor 1 family of proteins. The encoded cell surface receptor is activated through proteolytic cleavage of its extracellular amino terminus, resulting in a new amino terminus that acts as a tethered ligand that binds to an extracellular loop domain. Activation of the receptor has been shown to stimulate vascular smooth muscle relaxation, dilate blood vessels, increase blood flow, and lower blood pressure. This protein is also important in the inflammatory response, as well as innate and adaptive immunity. [provided by RefSeq, Jun 2016]

Product Specifications

Background

This gene encodes a member of the G-protein coupled receptor 1 family of proteins. The encoded cell surface receptor is activated through proteolytic cleavage of its extracellular amino terminus, resulting in a new amino terminus that acts as a tethered ligand that binds to an extracellular loop domain. Activation of the receptor has been shown to stimulate vascular smooth muscle relaxation, dilate blood vessels, increase blood flow, and lower blood pressure. This protein is also important in the inflammatory response, as well as innate and adaptive immunity. [provided by RefSeq, Jun 2016]

Specifications

This protein .

Accession Number

P55085

Expression Region

Ser 37 - Tyr 397

Host

HEK293

Target

PAR2

Conjugation

Unconjugated

Tag

-

Source

Human

Stability

The product MUST be stored at -70°C or lower upon receipt; -70°C for 12 months under sterile conditions.

Endotoxin

1.0 EU per μg

Bioactivity

Immobilized Human PAR2 Full Length Protein (VLP) (Cat. No. PA2-H52P7) at 5 μg/mL (100 μL/well) can bind Anti-PAR2 Antibody, Human IgG1 with a linear range of 1-39 ng/mL (QC tested).

Format

Liquid

Buffer

PBS, Arginine, pH7.4

Additives

Trehalose

Additionnal Information

Please see 'Shipping-and-Payments' sheet. Website: https://www.acrobiosystems.com/support/shipping-and-payments

Shipping Conditions

Dry ice

Storage Conditions

-70°C

Package Size

20ug*1

Host or Source

HEK293

Species

Human

Protein ID

P55085

Preservative

Trehalose

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