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SARS-CoV-2 (COVID-19) S protein RBD, His Tag

SARS-CoV-2 S protein RBD, His Tag (SPD-C52H1) is expressed from human 293 cells (HEK293) .

Product Specifications

Background

It's been reported that Coronavirus can infect the human respiratory epithelial cells through interaction with the human ACE2 receptor. The spike protein is a large type I transmembrane protein containing two subunits, S1 and S2. S1 mainly contains a receptor binding domain (RBD), which is responsible for recognizing the cell surface receptor. S2 contains basic elements needed for the membrane fusion.The S protein plays key parts in the induction of neutralizing-antibody and T-cell responses, as well as protective immunity.

Specifications

This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 26.5 kDa. The protein migrates as 32 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.

Accession Number

QHD43416.1

Host

HEK293

Target

Spike RBD

Conjugation

Unconjugated

Tag

C-10xHis

Source

SARS-CoV-2

Stability

● The product MUST be stored at -70°C or lower upon receipt; ● -70°C for 3 months under sterile conditions.

Endotoxin

1.0 EU per μg

Purity

95%

Bioactivity

Immobilized SARS-CoV-2 S protein RBD, His Tag (Cat. No. SPD-C52H1) at 1 μg/mL (100 μL/well) can bind Anti-SARS-CoV-2 Neutralizing Antibody, Human IgG1 (Cat. No. SAD-S35) with a linear range of 0.1-3 ng/mL (QC tested).

Format

Liquid

Buffer

10 mM PB, pH7.4

Molecular Weight

26.5 kDa

Shipping Conditions

Dry ice

Storage Conditions

-70°C

Package Size

200ug*1

Product Datasheet

Https://www.acrobiosystems.com/static/main/products/pdf/ds/SPD-C52H1.pdf

Species

SARS-CoV-2

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