Human latent GDF-8 Protein, His Tag (pro & latent) (MALS verified)
Human latent GDF-8, His Tag (GD8-H5243) is expressed from human 293 cells (HEK293) . It contains AA Asn 24 - Ser 375 (Accession # O14793-1) .
Product Specifications
Background
Growth differentiation factor 8 (GDF8), also known as myostatin, is a unique member of the transforming growth factor-β superfamily that is expressed in human granulosa cells and has important roles in regulating a variety of ovarian functions. GDF8 acts as a negative regulator of skeletal muscle growth and differentiation. In addition to the expression in the musculoskeletal system, GDF8 is also expressed in various tissues, including the reproductive system.
Specifications
This protein carries a polyhistidine tag at the N-terminus. The protein migrates as 14kDa, 35 kDa and 45-50 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE), speculated as latent GDF-8 and GDF-8 propeptide respectively due to glycosylation.
Accession Number
O14793-1
Expression Region
Asn 24 - Ser 375
Host
HEK293
Target
GDF-8
Conjugation
Unconjugated
Tag
N-10xHis
Source
Human
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
90%
Format
Powder
Buffer
PBS, 0.2 M Arginine, pH7.4
Additives
Trehalose
Molecular Weight
42.0 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
50ug*1
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/GD8-H5243.pdf
Species
Human
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