Human CCL5/RANTES Protein, Fc Tag (MALS verified)
Human CCL5, Fc Tag (CC5-H5251) is expressed from human 293 cells (HEK293) . It contains AA Ser 24 - Ser 91 (Accession # P13501-1) .
Product Specifications
Background
C-C chemokine ligand 5 (CCL5), also known as RANTES, is a target gene of NF-kappaB, and is expressed by T lymphocytes, macrophages, platelets, synovial fibroblasts, tubular epithelium, and certain types of tumour cells. CCL5 plays a role in recruiting a variety of leukocytes into inflammatory sites including T cells, macrophages, eosinophils, and basophils. CCL5 activity is mediated through its binding to CCR1, CCR3, and mainly CCR5.
Specifications
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 34.4 kDa. The protein migrates as 40 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
Accession Number
P13501-1
Expression Region
Ser 24 - Ser 91
Host
HEK293
Target
CCL5
Conjugation
Unconjugated
Tag
C-Fc
Source
Human
Stability
● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.
Endotoxin
1.0 EU per μg
Purity
95%
Bioactivity
Immobilized Human CXCL4, His Tag (Cat. No. CX4-H52H9) at 5 μg/mL (100 μL/well) can bind Human CCL5, Fc Tag (Cat. No. CC5-H5251) with a linear range of 0.156-2.5 μg/mL (QC tested).
Format
Powder
Buffer
50 mM Tris, 100 mM Glycine, 25 mM Arginine, 150 mM NaCl, pH7.5
Additives
Trehalose
Molecular Weight
34.4 kDa
Shipping Conditions
RT
Storage Conditions
-20°C
Package Size
250ug*4
Product Datasheet
Https://www.acrobiosystems.com/static/main/products/pdf/ds/CC5-H5251.pdf
Species
Human
Curated Selection
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