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Human Laminin 211 Protein, premium grade

Human Laminin 211 Protein, premium grade (LA8-H5263) is expressed from human 293 cells (HEK293) .

Product Specifications

Background

Laminin-α2 is a critical component of the laminin heterotrimer, which along with laminin-β1 or β2 and laminin-γ1 form the structural glycoproteins laminin-211 and laminin-221 in skeletal muscle. Laminin-211 is the most abundant laminin isoform in the basement membrane of adult skeletal muscle. Laminin-211 and -221 polymerize with each other and interact with nidogen and collagen-IV to form the muscle basal lamina. Laminin-211 and laminin-221 bind to muscle cell surface through the α7β1 integrin and α-dystroglycan of the dystrophin glycoprotein complex via their globular C-terminal domains.

Specifications

This protein .

Host

HEK293

Target

Laminin 211

Conjugation

Unconjugated

Source

Human

Stability

● -20°C to -70°C for 12 months in lyophilized state; ● -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower.

Endotoxin

0.1 EU per μg

Purity

90%

Bioactivity

Immobilized Human Laminin 211 Protein, premium grade (Cat. No. LA8-H5263) at 5 μg/mL (100 μL/well) can bind Human ITGA7X2B&ITGB1 Heterodimer Protein, His Tag&Tag Free (Cat. No. IT1-H52W8) with a linear range of 0.02-0.313 μg/mL (QC tested).

Format

Powder

Buffer

PBS, pH7.4

Additives

Trehalose

Shipping Conditions

RT

Storage Conditions

-20°C

Package Size

100ug*1

Product Datasheet

Https://www.acrobiosystems.com/static/main/products/pdf/ds/LA8-H5263.pdf

Species

Human

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