Monoclonal Anti-Monkeypox-A29L Antibody, Human IgG1 (3H9) (MALS verified)

Monkeypox is a rare zoonosis caused by monkeypox virus, which has become the most serious orthpoxvirus and consists of complex double stranded DNA. The pathogenesis of monkeypox is that the virus invades the body from respiratory mucosa, multiplies in lymphocytes, and incurs into blood producing transient venereal toxemia. after the virus multiplies in cells, the cells can invade the blood and propagate to the skin of the whole body, causing lesions. A29L binds to cell surface heparin to promote fusion of viral membrane with host plasma membrane.

Product Specifications

Background

CAS Number

9007-83-4

Host

HEK293

Origin Species

Human

Target

A29L (MPXV)

Conjugation

Unconjugated

Tag

Human IgG1 | Human Kappa

Stability

-20°C to -70°C for 12 months in lyophilized state; -70°C for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20°C or lower. Please avoid repeated freeze-thaw cycles.

Purity

0.9

Bioactivity

Immobilized Monkeypox virus (strain Zaire-96-I-16) A29L Protein, His Tag (Cat. No. A2L-M52H3) at 1 μg/mL (100 μL/well) can bind Monoclonal Anti-Monkeypox-A29L Antibody, Human IgG1 (3H9) (MALS verified) (Cat. No. A2L-M577) with a linear range of 0.5-16 ng/mL (QC tested).